ABSTRACT

Basic Information

Abstract Number: 2070 - 3
Author Name: Christy L Haynes - University of Minnesota
Session Title: Application of SERS Sensors to Biomedicine and the Environment
Event Type: Symposia
Event Title: SERS in Blood

Presider Name:John Rabolt
Affiliation:University of Delaware

Date: Thursday, March 6, 2014
Start Time: 09:10 AM (Slot #3)
Location: S401bc

Abstract Content

The complex and dynamic nature of biological systems necessitates rapid, label-free sensing platforms. Combining the chemical stability of mesoporous silica core shell nanomaterials and the chemical sensitivity of surface-enhanced Raman scattering (SERS)-active gold core nanoparticles presents an optimal platform for stable and reliable SERS sensing. Herein, novel core-shell mesoporous silica nanosensors were fabricated to encapsulate different morphologies of gold nanoparticles, including nanorods and nanosphere aggregates. The nanosensors were extensively characterized using several microscopic and spectroscopic techniques, and then SERS spectra were captured from analytes presented in a matrix of whole blood. The presented data will include considerations of sensitivity, selectivity, and stability of this novel core-shell sensing platform.