Young Investigator Award from Subdivision on Chromatography and Separation Chemistry of the Analytical Chemistry Division of the ACS
Wednesday, March 3rd, 2010
8:00 AM Room: 300

Organizers:
Brian A Bidlingmeyer, Agilent Technologies, Inc.

Speakers:
8:00 AMIntroductory Remarks -
8:05 AMPresentation
8:10 AMExpanding the Separations Toolbox: Capillary Separations with Enhanced Sensitivity and Selectivity for Interrogating Biomolecular Systems , Craig Aspinwall
8:45 AMCombined LC-LC-MS for the Separation and Identification of Proteins in Complex Mixtures, Brenna McJury
9:20 AMHigh Throughput Electrophoresis Using Droplets and Microfluidics, Robert Kennedy
9:55 AMRecess
10:10 AMMicrotechnologies to Analyze Single Cells, Nancy Allbritton
10:45 AMHigh-throughput, Ultrasensitive Isoelectric Focusing, Norman Dovichi


Overview:
The Analytical Chemistry Award for Young Investigators in Separation Science was instituted by the Subdivision of Chromatography and Separation Science, a subdivision of the Analytical Division of the American Chemical Society. It was established to recognize and encourage outstanding contributions to the field of separation science by a young chemist or chemical engineer who has earned his or her highest degree within ten years of January 1 of the year of the award.

The recipient of the 2010 Award is Craig A. Aspinwall of the University of Arizona. Craig has made leading edge contributions to separation science to answer questions in neuroscience. His group has made in real time on-line monitoring of neurotransmitters and hormones. In these endeavors, he has developed a novel approach for optical sample introduction in capillary separations which provides marked enhancements in sensitivity by markedly reducing the luminescence background. His ultra fast separations using photolysis of caged fluorescence dyes has achieved ultrahigh sensitivity of neurotransmitters and hormones with on-column detection limits as low as 5 pM.

A second contribution to separation science was to increase separation selectivity, through the development of a series of biomimetic separation media using polymeric phospholipid materials. The resulting polymer coating reduces non-specific protein adsorption, a major problem for capillary separations, and provides a platform for incorporation of specific binding interactions via functionalization. He has recently shown that transmembrane proteins can be incorporated into the highly stable polymeric phospholipid bilayers, therein providing for novel biomolecular interactions for separation systems.