|Abstract Number: ||580 - 7|
|Author Name: ||Bo Zhang - University of Washington|
|Session Title: ||SEAC - Charles N Reilley and Young Investigators Awards|
|Event Type: ||Awards|
|Event Title: ||Fluorescence-Enabled Electrochemistry and Single-Cell Imaging|
|Presider Name:||Henry White||Co-Author:||Joshua Guerrette, Stephen Percival, Jonathan Cox|
|Affiliation:||University of Utah||Affiliation:||University of Washington|
|Date: ||Monday, March 18, 2013|
|Start Time: ||04:00 PM (Slot #7)|
|We have developed a new electrochemical method called fluorescence-enabled electrochemical microscopy (FEEM). This method is|
based on the direct electrochemical coupling of two redox reactions on a bipolar electrode. In FEEM, a redox analyte is electrochemically oxidized on the anodic pole of a bipolar electrode. This oxidation reaction is coupled to a fluorogenic redox reaction on the cathodic pole, which can be optically detected using fluorescence microscopy.
In this talk, I will focus on the fundamental aspects of electrochemical coupling on a closed bipolar microelectrode and how it enables us to perform better and faster measurements using carbon-fiber microelectrodes. I will then introduce our current research on using FEEM and microelectrode arrays to study transport of redox species and electrocatalyst screening. I will briefly discuss how FEEM can be used to better understand single-cell exocytosis and neuron-neuron communication.