Basic Information

Abstract Number: 580 - 7
Author Name: Bo Zhang - University of Washington
Session Title: SEAC - Charles N Reilley and Young Investigators Awards
Event Type: Awards
Event Title: Fluorescence-Enabled Electrochemistry and Single-Cell Imaging

Presider Name:Henry WhiteCo-Author:Joshua Guerrette, Stephen Percival, Jonathan Cox
Affiliation:University of UtahAffiliation:University of Washington

Date: Monday, March 18, 2013
Start Time: 04:00 PM (Slot #7)
Location: 114

Abstract Content

We have developed a new electrochemical method called fluorescence-enabled electrochemical microscopy (FEEM). This method is
based on the direct electrochemical coupling of two redox reactions on a bipolar electrode. In FEEM, a redox analyte is electrochemically oxidized on the anodic pole of a bipolar electrode. This oxidation reaction is coupled to a fluorogenic redox reaction on the cathodic pole, which can be optically detected using fluorescence microscopy.

In this talk, I will focus on the fundamental aspects of electrochemical coupling on a closed bipolar microelectrode and how it enables us to perform better and faster measurements using carbon-fiber microelectrodes. I will then introduce our current research on using FEEM and microelectrode arrays to study transport of redox species and electrocatalyst screening. I will briefly discuss how FEEM can be used to better understand single-cell exocytosis and neuron-neuron communication.