Basic Information

Abstract Number: 2580 - 7
Author Name: W Christopher Siegler - The Dow Chemical Company
Session Title: ACS Separations Sciences Subdivision - New Voices in Separation Science: Up and Coming Scientists from Industry, Government and Academia
Event Type: Symposia
Event Title: Reverse Fill/Flush Flow Modulated GC×GC Coupled with Vacuum UV Detection: A Step towards Making Class Separation and Quantification a Routine?

Presider Name:Karen W PhinneyCo-Author:Anna Sandlin, Bill Winniford, Jeremy Reyes, Kefu Sun, James Griffith, Phillip Walsh, Dale Harrison
Affiliation:National Institute of Standards and Technology (NIST)Affiliation:The Dow Chemical Company, VUV Analytics Inc.

Date: Thursday, March 12, 2015
Start Time: 04:10 PM (Slot #7)
Location: 238

Abstract Content

Complex samples with multiple compound classes present, compound similarity (isomers), and a wide range of analyte concentrations all present a challenge to conventional gas chromatographic (GC) separation techniques. One powerful technique for the analysis of complex samples is comprehensive two-dimensional gas chromatography (GC×GC). Another is a recently developed vacuum UV (VUV) detector that can be coupled to a GC and is capable of collecting full spectral scans from 125 to 240 nm on the millisecond time scale with less than 1 nm spectral resolution. VUV spectra can be compared to reference spectra, although relatively few are available, compared to known experimental standards, or predicted by molecular modeling to confirm structure. The VUV detector is capable of providing compound quantification as well. The VUV has shown promise in differentiating chemical classes, some of which include: alcohols, aldehydes, esters, acids, glycol ethers, amines, thiols, sulfides, chlorinated aliphatics. Use of specific spectral ranges can aid selective detection of certain compounds or enhance detector sensitivity. The combination of the new VUV detector with a GC×GC instrument may provide the next step towards ‘routine’ analysis of complex samples in regards to class separation and quantification. In this presentation, the coupling of a VUV detector with a reverse fill/flush flow modulation (RFF) comprehensive GC×GC instrument for selected industrial applications will be presented.