The Pittsburgh Spectroscopy Award
Sanford Asher, The University of Pittsburgh
01:30 PM Introductory Remarks -
01:35 PM Presentation
01:40 PM Bioinorganic Spectroscopy: Activating Metal Sites for Biological Electron Transfer
02:15 PM Synchrotrons and X-Ray Free Electron Lasers in Structural Biology – From “Slow” to “Ultrafast”
02:50 PM Spectroscopic Insights into the BioSynthesis of Coenzyme B12
03:25 PM Recess
03:40 PM Electron-Nuclear Double Resonance (ENDOR) in Metallobiochemistry
04:15 PM Dynamics and Mechanisms of Copper-Responsive Regulators and Efflux Pumps in Living Cells Revealed by Single-Molecule Imaging
Edward I Solomon, Stanford University, will receive the 2017 Pittsburgh Spectroscopy Award. This award was established in 1957 and honors an individual who has made outstanding contributions in the field of spectroscopy.
Edward I Solomon received his Ph.D. at Princeton, and was a postdoctoral fellow at the ěrsted Institute in Denmark and then at Caltech. He was a Professor at the Massachusetts Institute of Technology until 1982, when he joined the faculty at Stanford University, where he is now the Monroe E. Spaght Professor of Chemistry and Professor of Photon Science at SLAC. Professor Solomon’s research is in the fields of Physical–Inorganic and Bioinorganic Chemistry with emphasis on the application of a wide range of spectroscopic methods combined with QM calculations to elucidate the electronic structure of transition metal sites and its contribution to physical properties and reactivity.
Metal ions play critical roles in biological function and malfunction. The focus of this half day symposium is on the application of transition metal ion centered methods in defining structure/function correlations over metal sites in biology. Emphasis is both on a wide range of spectroscopies and on new structural methods that determine the geometric and electronic structures of metalloenzyme active sites, their reactivities in function and their dynamics in regulation. The techniques presented include spectroscopies extending over ten orders of magnitude in photon energy, single molecular microscopy and ultrafast x-ray crystallography.