ABSTRACT

Basic Information

Abstract Number: 650 - 7
Author Name: Alex M Aravanis - GRAIL
Session Title: The Twenty-Eighth James L Waters Symposium on Genomic Analysis Technologies
Event Type: Symposia
Event Title: Circulating Cell-Free Nucleic Acids and Early Cancer Detection

Presider Name:Adrian C Michael
Affiliation:The Pittsburgh Conference

Date: Monday, March 6, 2017
Start Time: 04:10 PM (Slot #7)
Location: W183c

Abstract Content

The obstacles to developing a safe and effective cancer screening tests are numerous, including biological, technical, and clinical challenges. The development of new tools that directly measure the sin qua non of cancer (its somatic alterations) has created new possibilities for methods of cancer detection. In particular, low-cost next generation sequencing has enabled the sequencing of tumor-derived nucleic acids circulating in the blood. This non-invasive characterization of a tumor’s genome combined with new methods of processing complex data may enable sensitive and specific detection of lethal cancers when they are still curable through surgery.