Course Information
Course Title: Physical Chemistry of Macromolecules, Part II - Methods of Analysis
Categories: 1 - Infrared Spectroscopy
2 - Liquid Chromatography
3 - Polymers
4 - Spectroscopy
Instructor(s): Bernhard Dringenberg Course Number: 53
Affiliation: LAT
Course Date: 03/12/2012 - Monday Course Length: 1/2 Day Course
Start Time: 01:00 PM End Time: 05:00 PM
Fee: $235 ($335 after 2/13/12) Textbook Fee:

Course Description
Physical Chemistry of Macromolecules is presented in three parts. Part II, this course is meant for the analysis of macromolecules. Optical, chromatographic, electrophoretical, spectroscopical and mathematical subjects are presented to investigate the physico-chemical parameters of macromolecules.

Target Audience
Students of chemistry, chemical engineering as well as technical employers who like to understand in more detail how to handle macromolecules in industrial processes or for scientific research.

Course Outline
1. Liquid Crystals: Polymeric Liquid Crystals Liquid-Crystal Phases Kerr Effect Theories of Liquid-Crystalline Ordering Current Industrial Applications of Liquid Crystals
2. Protein Molecules Sequences and Structure Alpha-Helix and Beta-Sheet Tertiary and Quarternary Structure Protein Folding and Refolding Protein Misfolding Genomics, Proteomics, and Bioinformatics
3. Optical Rotary Dispersion and Circilar Dichroism: Polarized Light Optical Rotary Dispersion Circular Dichroism Cotton EffectCorrelation Between ORD and CD
4. High-Performance Liquid Chromatography and Electrophoresis: Chromatographic Terms and Parameters and Theory Basic Theory of Electrophoresis and General Techniques Southern Blot, Northern Blot, and Western Blot Sequencing DNA FragmentsIsoelectric Focussing and IsotachophoresisField-Flow Fractionation
5. Light Scattering:Rayleigh ScatteringFluctuation Theory (Debye) Internal Interference Determination of Molecular Weight and Radius of Gyration of the Zimm Plot
6. Electronic and Infrared Spectroscopy: Ultraviolet and Visible Absorption Spectra Lambert-Beer LawSynthetic Polymers, Proteins, Nucleic Acids Fluorescence Spectroscopy Emission and Excitation Spectra Quenching and Energy Transfer Polarization and Depolarization Basic Theory of Infrared Spectroscopy Infrared Spectroscopy of Synthetic Polymers and Biological PolymersFourier Transform Infrared Spectroscopy
7. Fourier Series: Conversion of Infinite Series into Integrals Fourier Integrals and Transforms Convolution Theorem Lorentz Line Shape Discrete and Inverse Discrete Fourier Transform

Course Instructor's Biography
Bernhard J. Dringenberg, earned his Ph.D. at the Max-Planck-Institute of Biophysical Chemistry in Göttingen. His main interests are the physical chemistry of nanoparticles and macromolecules meant for application in pharmaceuticals, biomaterials, photocatalists, and surface sciences.