Course Information
Course Title: Solid-Phase Microextraction
Categories: 1 - Liquid Chromatography-Mass Spectrometry
2 - Clinical Analysis
3 - Environmental Analysis
4 - Sample Preparation
5 - Food
6 - Gas Chromatography-Mass Spectrometry
Instructor(s): Barbara Bojko Course Number: 44
Affiliation: Department of Chemistry, University of Waterloo
Course Date: 03/11/2012 - Sunday Course Length: 1 Day Course
Start Time: 08:30 AM End Time: 05:00 PM
Fee: $455 ($655 after 2/13/12) Textbook Fee: $100

Course Description
Solid-phase microextraction (SPME) is a simple, fast, sensitive, and environmentally-friendly sample preparation technique that integrates sampling and sample preparation steps. This course will cover the main principles of SPME, calibration methods, coupling strategies of SPME to GC and LC and method development strategy. Applications of SPME in the fields such as forensic, environmental, food and beverage and clinical analysis will be discussed. Advances in SPME will be highlighted including: ligand-receptor binding and plasma protein binding studies, in vivo sampling of freely moving animals for pharmacokinetic and metabolomic studies, automation in high-throughput format and direct tissue analysis.

Target Audience
The course is targeted at new and current SPME users. It will be of interest to analytical chemists, laboratory supervisors, scientists and industry regulators in the environmental, food and beverage, pharmaceutical, clinical, cosmetic and other fields. The features of in vivo SPME sampling will be of particular interest to biologists and life scientists.

Course Outline
Introduction to SPME
Theoretical principles of SPME
SPME interfaces
Calibration of SPME
SPME method development
Automation of SPME
In vivo sampling using SPME
Drug and clinical analysis
Food, flavor and fragrance analysis
Environmental analysis

Course Instructor's Biography
Dr. Barbara Bojko obtained her medical diagnostician diploma, MSc and PhD (Hon) from pharmaceutical sciences with the specialization in pharmaceutical biochemistry. She is the author of 30 journal publications. She has ten years of academic research and teaching experience. She was awarded several times for scientific achievements in the field of ligand-receptor interactions. Currently, as a postdoctoral fellow in Professor Janusz Pawliszyn’s group her research is focused on biomedical applications of SPME, especially on drug monitoring therapy and metabolomics. Dr. Janusz Pawliszyn is the inventor of SPME and a professor in the Department of Chemistry, University of Waterloo, Canada. He is the author of over 350 journal publications, 20 book chapters, and over 250 invited/plenary lectures. He has received several prestigious awards for his scientific achievements, and SPME is considered one of the six “Great Ideas of a Decade” by ACS Analytical Chemistry journal. He presently holds the Canada Research Chair and NSERC Industrial Research Chair in New Analytical Methods and Technologies.