Short Course Listings
 
Short Course

Course Information
Course Title: Analytical Ionic Liquids in GC and Mass Spectrometry
Categories: 1 - Mass Spectrometry
2 - Gas Chromatography
3 - Gas Chromatography-Mass Spectrometry
4 - Green Chemistry
Instructor(s): Leonard Sidisky, Daniel Armstrong Course Number: 70
Affiliation: SIGMA ALDRICH CORPORATION-
Course Date: 03/07/2016 - Monday Course Length: 1/2 Day Course
Start Time: 01:00 PM End Time: 05:00 PM
Fee: $300 ($400 after 2/12/16) Textbook Fee:

Course Description
Ionic liquids have received considerable interest as new green solvent systems in the areas of organic reactions and separation technologies along with a number of other areas. These materials are a class of non-molecular solvents that consist of essentially organic cations and anions. They have been found to possess negligible volatility, non-flammability, high thermal stability, and low melting points. There are numerous combinations of cations and anions possible, so tailoring the material to a specific application or function is a potential benefit of these materials. The session will focus on the utility of ionic liquids in a number of areas of separation science including sample preparation for gas and liquid chromatography, as phases for GC, as additives for HPLC, and the use of ionic liquids with mass spectrometry when used as stationary phases for capillary gas chromatography, as liquid MALDI matrices and as ion pairing agents for the positive ion mode detection of anions by ESI-MS analysis.

Target Audience
Analysts interested in the use of ionic liquids for various chromatographic, sample prep and mass spectroscopy analyses. The unique properties of ionic liquids offer many new opportunities for green chemistry.

Course Outline
1. Overview of the Structure, Properties & Uses of Ionic Liquids - Dan Armstrong
2. Characterization of Ionic Liquid Stationary Phases for Capillary Gas Chromatography - Len Sidisky
3. Ionic Liquid Based Analysis of Water - Dan Armstrong
4. Capillary Gas Chromatography Applications of Ionic Liquid Stationary Phases - Len Sidisky

Course Instructor's Biography
Leonard M. Sidisky Research & Development Manager for Gas Separations at Supelco, Division of Sigma-Aldrich. He received his B.S. degree in Biology (1980) and an M.S. in Food Science (1997) from The Pennsylvania State University. He has been working at Supelco since 1982 and is responsible for the research and development of new novel technologies related to gas chromatography, sample preparation, air sampling, solid phase microextraction and high performance carbon adsorbents. His analytical background includes expertise in Gas Chromatography, Liquid Chromatography, Sample Preparation devices such as Solid Phase Extraction (SPE), and Solid Phase Microextraction (SPME). He is a member of the American Oil Chemist’s Society (AOCS), AOCS Analytical Division, AOCS Northeast Section, AOCS Chromatography Committee Chairperson 2000-2009, AOCS Governing Board Technical Steering Committee Chairperson 2010-present, AOCS Northeast Section president 2000-2001, vice president 1998-1999, Hans Kaunitz Award Chairman 2000-2001, Supelco/ Nicholas Pelick AOCS Lipid Award Representative 1994-present, 1992 Ralph H. Potts Memorial Fellowship Award Winner. He is also a member of the Institute of Food Technologists (IFT) professional member 1992-present, American Chemical Society (ACS) member 1982-present; ASTM D16 (Aromatic Hydrocarbons) 1990-present, D16.OE.09 Task Group (Capillary Applications) chairman 1995-present and ASTM E13 Committee His research interests are in the development of Gas Chromatographic products for wide range of industrial applications, capillary columns for lipid sample analyses, theory and practical application of Capillary Gas Chromatography and Solid Phase Micro Extraction (SPME) product development and applications. He has presented numerous papers and seminars worldwide and has published over 25 journal articles. Daniel W. Armstrong is the Robert A. Welch Professor of Chemistry at the University of Texas at Arlington. He has over 600 publications including 29 book chapters, one book ("Use of Ordered Media in Chemical Separations") and 30 patents. He has given over 550 invited seminars and colloquia worldwide. He first developed cyclodextrims, macrocyclic antibiotics and cyclofructans as chiral selectors. He is one of the world's leading authorities on the theory, mechanism and use of enantioselective molecular interactions. His work and columns were in part responsible for the chromatography and electrophoresis - lead revolution in chiral separations over the last two decades. This work provided the impetus for the FDA’s regulatory changes regarding chiral drug development in 1992. He also developed the most comprehensive solvation and characterization models for room temperature ionic liquids (RTILs) and pioneered their use in analytical chemistry (separations and mass spectrometry). More recently, he has developed rapid, high efficiency, microfluidic methods for analyzing microorganisms and colloidal particles. Professor Armstrong has received over 25 national, international research and teaching awards. His current research involves chiral recognition, specific separation and detection of enantiomers, cyclodextrin chemistry, investigation of biologically active molecules, macrocyclic antibiotics, and high efficiency microbial analysis, and use of room temperature ionic liquids in chemical analysis and separations. He also has interests in a variety of other areas from oceanography to gemstone analysis. The bio-tech company, Advanced Separation Technologies, Inc. (a.k.a. Astec), was jointly formed by Professor Armstrong and his colleagues in 1983, and acquired in 2006 by Aldrich/Sigma/Supelco, which is the largest specialty chemical company in the world. His new company (AZYP, LLC) specializes in new chiral and HILIC LC columns and cyclofructan development. He also was on the Scientific Advisory Board of three corporations and one university.