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Short Course

Course Information
Course Title: Practical Gas Chromatography
Categories: 1 - Petroleum Analysis
2 - Pharmaceutical Sciences
3 - Environmental Analysis
4 - Gas Chromatography
Instructor(s): Eugene Barry / Thomas Brettell Course Number: 92
Affiliation: UMass Lowell / Cedar Crest College
Course Date: 03/05/2016 - Saturday Course Length: 2 Day Course
Start Time: 08:30 AM End Time: 05:00 PM
Course Date 2: 03/06/2016 - Sunday    
Start Time: 08:30 AM End Time: 05:00 PM
Fee: $1050 ($1450 after 2/12/16) Textbook Fee: $160

Course Description
This course will present the fundamentals of gas chromatography with an emphasis on practical applications for users and method developers. Topics to be covered include theoretical considerations, uses of computer searches for literature references and methods of analysis, modern instrumentation, including inlet, column and detector technologies, fast GC and the application of these to effective qualitative and quantitative analysis. The theoretical portion of the course will focus on using the fundamental understanding of the chromatographic process (limited number of equations and comparisons to extractions and distillations) to assist in obtaining a desired separation quality and run time. Modern instrumentation including split, splitless, on-column, and programmed-temperature inlets and electronic pressure control will be discussed. Emphasis will also be placed on selective detectors , including TCD, FID, PID, ECD, Hall ECLD and GC/MS. Finally all of this will be applied to practical problems in qualitative and quantitative analysis.

Target Audience
This course represents a balanced blend of pertinent information and underlying theory for successful practice of gas chromatography. Individuals working in the area of gas chromatography, beginners and those desiring to update their knowledge of the technique will find this course to be meaningful and useful.

Course Outline
DAY 1-MORNING

Evolution of Chromatography, IUPAC Nomenclature
Similarities to Extractions & Distillations
Theory of Gas Chromatography-Plate and Rate Theories
Effect of Changing Conditions on Peak Separations

DAY 1-AFTERNOON
INLETS/MOBILE PHASES:
Injection Modes & Mobile Phases, Instrumental requirements for Capillary Columns
Capillary Column Inlets (Split, Splitless, On-Column, Direct Injection, Electronic Pressure Control
Programmed-Temperature Vaporizer, Large Volume Injections
DAY 2-MORNING

GAS CHROMATOGRAPHIC COLUMNS
Classification and Selection of Stationary Liquid Phases and Adsorbents
Capacity and Analysis Time, Capillary Column Selection
Chromatographic Parameters Affecting Column Performance
Effect of Capillary Column ID, Film Thickness,and Length
Fast Gas Chromatography
Capillary Column Rinsing, Rejuvenation, Care and Maintenance, Columns for Special Applications: Ionic Liquids, PLOT, Chiral and Methods: EPA, OSHA, ASTM, USP

DAY 2-AFTERNOON
COMPUTER ASSISTANCE IN GAS CHROMATOGRAPHY
Internet-Guidance and Resources
Software for Prediction and Optimization of Separations
DETECTORS

Fundamentals and Parameters Affecting Detector Response,
Types of Detectors Detectors Used for Various Analyses


QUALITATIVE & QUANTITATIVE ANALYSIS
Qualitative Analysis
Quantitative Analysis Methods

ANCILLARY SAMPLE INTRODUCTION TECHNIQUES
Pyrolysis
Solid-Phase Microextraction (SPME)

TROUBLESHOOTING AND DISCUSSION

Course Instructor's Biography
Dr. Eugene F. Barry is Professor Emeritus of Chemistry and former Chair of the Chemistry Department at the University of Massachusetts Lowell. He received his B.S. in Chemistry from Villanova University (1967) and a Ph.D. in Analytical Chemistry from the University of Rhode Island (1970). He is a recipient of the Most Outstanding Teaching Award at UMass Lowell. In collaboration with the late Robert L. Grob, he is co-editor of Modern Practice of Gas Chromatography, Fourth Edition and co-author of the book, Columns for Gas Chromatography: Performance and Selection, both published by John Wiley. During his tenure at the University of Massachusetts Lowell, Dr. Barry has taught a wide variety of courses in Analytical Chemistry, including graduate level courses in chromatography and separation methods, his primary area of research. His current research interests include GC-MS, computer-assisted optimization of separations by capillary GC, high-speed gas chromatography, enhanced oil recovery in addition to geological and oceanic sequestration of carbon dioxide and the determination of organics in challenging matrices, such as cement and concrete. He is author of over 100 research publications and several patents. Thomas A. Brettell retired as the Director of the New Jersey State Police Office of Forensic Sciences and is presently an Associate Professor of Chemistry in the Chemical and Physical Sciences Department at Cedar Crest College. Dr. Brettell’s main research areas are in chromatography and medico-legal aspects of alcohol. His Ph.D. thesis was in the area of Headspace Gas Chromatographic analysis of fire debris accelerants. He has taught advanced separation courses including headspace gas chromatography and the gas chromatography course sponsored by the Chromatography Forum of the Delaware Valley. In 1993, he received a commendation from the NJSP Superintendent for his work on a narcotics investigation. Dr. Brettell is a past Chair of the Criminalistics Section of the American Academy of Forensic Sciences and a past President of the Chromatography Forum of the Delaware Valley. Tom was presented the Chromatography Forum of the Delaware Valley Award in 1997 for service to the Forum and accomplishments in the field of separation science and also served on the Advisory Board of the Journal of Analytical Chemistry from 1996 to 1998. In 2004, Dr. Brettell was appointed to the Governor’s Advisory Council Against Sexual Violence and served until 2006. He presently serves on the National Safety Council’s Committee on Alcohol and Other Drugs. Dr. Brettell is a certified Diplomat of the American Board of Criminalistics and a Fellow in the American Academy of Forensic Sciences.