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Short Course

Course Information
Course Title: Method Translation in Gas Chromatography to get the Same Chromatogram
Categories: 1 - Gas Chromatography
2 - Gas Chromatography-Mass Spectrometry
Instructor(s): Jaap de Zeeuw Course Number: 62
Affiliation: Restek
Course Date: 03/07/2016 - Monday Course Length: 1/2 Day Course
Start Time: 01:00 PM End Time: 05:00 PM
Fee: $300 ($400 after 2/12/16) Textbook Fee:

Course Description
In Gas chromatography there is often a need to optimize separations using different column dimensions, different linear gas velocity, using a different detector or using a different carrier gas. If you want to get the same peak elution order (same chromatogram), you must make sure that the elution temperatures of components is kept the same. This is only possible using a different oven temperature program. To calculate this program, there are free calculation programs available on the web. In this course we will discuss the details of conversion of methods so you get the same chromatograms with the new method.

Target Audience
This short course is intended for the user of GC equipment that is able and want to learn to modify methods to improve lab efficiency. For maximum result, some experience with GC separations and analytical chemistry is preferred

Course Outline
In this half day course we will discuss the basics of converting existing GC methods into a new (mostly faster) method, and aiming for the same separation / peak elution order. If column dimensions, linear velocity or pressure drop over a capillary column is changed, and without changing temperature program, the separation of many components will change. Some separations will be better, some will go worse. In order to keep the separation similar, one needs to adjust the oven temperature, to get the same elution temperatures. For this, one can use free calculation programs, available on the web. The different options of these calculation programs will be explained and demonstrated. It is recommended to bring a laptop to join hands on experience.

Course Instructor's Biography
Jaap de Zeeuw studied 6 yrs of chemistry and graduated in 1979; His thesis was entitled “Fused Silica Capillary Column Technology”; Jaap has 36 years experience in GC capillary technology, developed many PLOT columns as well as bonded phase columns. He is also the originator for simple concepts for fast GC/MS using a high vacuum inside the capillary column. Jaap has traveled widely and is well known for his technical expertise and teaching skills. Jaap has published more then 100 publications in the field of GC on column technology and application. Jaap worked 27 years for Chrompack/Varian and presently serves the last 9 years as an international specialist on gas chromatography for Restek in the Netherlands, involved with product development, application and teaching chromatography.