Short Course Listings
Short Course

Course Information
Course Title: Chiral Separations
Categories: 1 - Liquid Chromatography
2 - Chiral Separations
3 - Pharmaceutical Sciences
4 - Enantiomeric Separations
5 - Gas Chromatography
6 - Supercritical Fluid
Instructor(s): Zachary Breitbach, Daniel Armstrong Course Number: 102
Affiliation: AbbVie
Course Date: 03/05/2017 - Sunday Course Length: 1/2 Day Course
Start Time: 08:30 AM End Time: 12:30 PM
Fee: $325 ($425 after 2/18/17) Textbook Fee:

Course Description
The goal of the “chiral separations” short course is to familiarize the participants with the best available options when confronted with the need for chiral separations. The course format allows for the dissemination of a considerable amount of information in an interesting and informal manner. Attendees can expect to gain an in-depth knowledge of chirality, the different means to separate enantiomers, and when / how to apply different state-of-the-art techniques. There will be a question and answer session at the conclusion of the course and participants are encouraged to ask any question related to the course as well as discuss current chiral separations challenges in their laboratory.

Target Audience
The course is designed for researchers faced with separation or analysis of enantiomeric compounds. The material is broadly applicable and useful for researchers in industry (e.g. pharmaceutical, agrochemical, etc…), as well as, academic researchers. Participants should have a basic knowledge of chromatography and experience with routine achiral GC and HPLC.

Course Outline
The first part of the course will include a review of the terminology of chirality and a brief overview of the theory behind enantiomeric separations (30 min). Then a summary of all HPLC techniques will be presented (70 min). The second half of the course will focus on new HPLC chiral selectors and method development (60 min) with a final focus on supercritical fluid (SFC) separations (40 min). The last discussion topic will cover capillary based enantiomeric separations by GC and CE (30 min).

Course Instructor's Biography
Daniel W. Armstrong is the Robert A. Welch Professor of Chemistry at the University of Texas at Arlington. He has over 550 publications including 29 book chapters, one book ("Use of Ordered Media in Chemical Separations") and 23 patents. He is considered the "Father" of pseudophase (micelle and cyclodextrin-based) separations. He elucidated the first chiral recognition mechanism for cyclodextrins. He also first developed macrocyclic antibiotics and cyclofructans as chiral selectors. He is one of the world's leading authorities on the theory, mechanism and use of enantioselective molecular interactions Zachary Breitbach obtained his Bachelor of Science degree in chemistry from Clarke College in 2005. He received his Doctor of Philosophy degree in analytical chemistry from The University of Texas at Arlington under the direction of Professor Daniel Armstrong in 2010. He continued his career at UTA serving as a Research Scientist where he helped develop new chiral stationary phases for HPLC, SFC and GC. He also served as a consultant to AZYP, LLC regarding new chemical separation media focused on chiral and HILIC HPLC separations. Currently, Dr. Breitbach is a Senior Scientist at AbbVie. He has published approximately 60 peer-reviewed research manuscripts, holds 3 patents, and has presented work at numerous research conferences.