Basic Information
Poster Number: 860-8    
Author Name: Paul Anthony Ullucci Affiliation: Thermo Fisher Scientific
Session Title: Pharmaceutical LC, HILIC and GPC I
Event Type: Poster
Event Title: The Spectro-Electro Array: A Novel Platform for the Measurement of Secondary Metabolites in Botanicals, Supplements, Foods and Beverages - Part 3: Metabolomics
Presider(s):   Start Time: ( Slot # 8 )
Date: Monday, March 12th, 2012 Location: Red Area on Exposition Floor, Aisles 1300-1500
Keywords: Electrochemistry, Pattern Recognition, Metabolomics, Metabonomics

Acworth, Ian NielThermo Fisher Scientific
Bailey, Bruce AThermo Fisher Scientific
Crafts, ChristopherThermo Fisher Scientific
Plante, MarcThermo Fisher Scientific

Abstract Content
Plants contain an extraordinarily diverse range of secondary metabolites including polyphenols, alkaloids, and terpenoids. Although these compounds are not involved in normal growth, development and reproduction, they still play a crucial role in the organism. For example, polyphenols act as pigments and can protect against disease. Secondary metabolites are also thought to be responsible for the purported health benefits associated with the consumption of botanicals, supplements, some foods and beverages. Interestingly, polyphenols are also associated with the quality and sensory characteristics of wine.

Gradient HPLC with spectro-electro array detection is both selective and sensitive and can be used to measure hundreds of known and unknown secondary metabolites in a sample. Such metabolite profiles contain a wealth of useful information. Changes in the pattern of metabolites, when evaluated using chemometric modeling software, can be used to study: product adulteration, contamination, composition, and stability, and in the case of wine and fruit juice, the effects of growing region and differences between varietals. The application of this metabolomic approach to wine, fruit juice adulteration and botanicals will be discussed in greater detail.